Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25260710 | 0.82 | POLH (0.72) | POLHKDM4EMEN1CYP3A4ALOX5 | |
| SCHEMBL30663840 | 0.78 | POLH (1.00) | POLHKDM4EMEN1CYP3A4ALOX5 | |
| SCHEMBL25263266 | 0.78 | POLH (1.00) | POLHKDM4EMEN1CYP3A4ALOX5 | |
| SCHEMBL25307372 | 0.75 | ABCG2 (0.67) | MEN1MAPTKMT2A | |
| SCHEMBL19745225 | 0.75 | HTR2B (0.57) | POLHMEN1MAPTKMT2AAR | |
| SCHEMBL21174972 | 0.74 | POLH (0.54) | POLHMEN1ALOX5KMT2A | |
| SCHEMBL8121953 | 0.72 | AR (0.62) | POLHKDM4EMEN1CYP3A4ALOX5 | |
| SCHEMBL2773475 | 0.72 | KDM4E (0.60) | POLHKDM4EMEN1CYP3A4ALOX5 | |
| SCHEMBL25308060 | 0.71 | POLH (0.60) | POLHKDM4EMEN1CYP3A4ALOX5 | |
| SCHEMBL24248100 | 0.71 | POLH (0.56) | POLHMEN1CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215522-A1 | DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF | Fondazione Istituto Italiano di Tecnologia (IT) | 2023-07-26 | — | — | EP | disclosed |