Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25306301 | 0.84 | ABCG2 (0.63) | ABCG2ABCB1ACHEMAPTNAMPT | |
| SCHEMBL25263149 | 0.84 | ABCG2 (0.61) | ABCG2ABCB1ACHEMAPTRAB9A | |
| SCHEMBL5277697 | 0.83 | ABCG2 (0.62) | ABCG2ABCB1ACHEMAPTHTT | |
| SCHEMBL5277304 | 0.80 | ABCG2 (0.59) | ABCG2ABCB1ACHEMAPTHTT | |
| SCHEMBL30663838 | 0.80 | KMT2A (0.69) | ABCG2ABCB1ACHEMAPTNPC1 | |
| SCHEMBL25308135 | 0.80 | KMT2A (0.69) | ABCG2ABCB1ACHEMAPTNPC1 | |
| SCHEMBL30506423 | 0.77 | ALDH1A1 (0.58) | ABCG2ABCB1ACHEMAPTNPC1 | |
| SCHEMBL29393931 | 0.76 | ALDH1A1 (0.57) | ABCG2ABCB1ACHEMAPTNPC1 | |
| SCHEMBL25840704 | 0.75 | POLH (0.63) | MAPTMEN1KMT2A | |
| SCHEMBL25306660 | 0.75 | ABCG2 (0.52) | ABCG2ABCB1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215522-A1 | DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF | Fondazione Istituto Italiano di Tecnologia (IT) | 2023-07-26 | — | — | EP | disclosed |