SCHEMBL25840940

SCHEMBL25840940

O=C(NC[SH](=O)=O)Nc1ccc(C(F)(F)F)cc1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.68
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
MTOR P42345 4/20 0.61
NAMPT P43490 1/20 0.60
CNR1 P21554 1/20 0.56
MAPT P10636 2/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
BAZ1A Q9NRL2 1/20 0.51
RAB9A P51151 2/20 0.50
KIF11 P52732 1/20 0.50
TGM2 P21980 1/20 0.50
RORC P51449 1/20 0.50
NPC1 O15118 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25841137 0.82 CDK1 (0.65) EPHX2MEN1KMT2AMTORNAMPT
SCHEMBL25841134 0.82 EPHX2 (0.51) EPHX2MEN1KMT2AMTORNAMPT
SCHEMBL28729179 0.82 EPHX2 (1.00) EPHX2MEN1KMT2AMTORNAMPT
SCHEMBL11003408 0.82 EPHX2 (1.00) EPHX2MEN1KMT2AMTORNAMPT
SCHEMBL28728293 0.81 MEN1 (0.77) EPHX2MEN1KMT2AMTORNAMPT
SCHEMBL13480539 0.81 MEN1 (0.77) EPHX2MEN1KMT2AMTORNAMPT
SCHEMBL23328422 0.80 EPHX2 (0.68) EPHX2MEN1KMT2AMTORNAMPT
SCHEMBL25841012 0.80 EPHX2 (0.68) EPHX2MEN1KMT2AMTORNAMPT
SCHEMBL18485933 0.79 MEN1 (0.68) EPHX2MEN1KMT2AMTORNAMPT
SCHEMBL136432 0.79 MEN1 (0.72) EPHX2MEN1KMT2AMTORNAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11701333-B2 Antibacterial compounds Kent Innovation & Enterprise (GB) 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11701333-B2 Antibacterial compounds ARF1, ARL1, TLR1 EPHX2 2581/4885MEN1 1300/4885KMT2A 2533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.