Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815349 | 0.92 | MEN1 (0.53) | MEN1TP53KMT2AMAPTRECQL | |
| SCHEMBL4815339 | 0.92 | MEN1 (0.53) | MEN1TP53KMT2AMAPTRECQL | |
| SCHEMBL28239649 | 0.87 | ALDH1A1 (0.43) | MEN1TP53KMT2AMAPTRECQL | |
| SCHEMBL2899860 | 0.82 | MEN1 (0.80) | MEN1TP53KMT2AMAPTRECQL | |
| SCHEMBL15451912 | 0.80 | ALDH1A1 (0.56) | MEN1TP53KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17809482 | 0.80 | ALDH1A1 (0.54) | MEN1TP53KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11741744 | 0.79 | MEN1 (0.85) | MEN1TP53KMT2AMAPTRECQL | |
| Hydrochloric Acid SCHEMBL27660773 | 0.79 | MEN1 (0.76) | MEN1TP53KMT2AMAPTRECQL | |
| Hydrochloric Acid SCHEMBL28000052 | 0.79 | MEN1 (0.76) | MEN1TP53KMT2AMAPTRECQL | |
| SCHEMBL13450558 | 0.78 | ALDH1A1 (0.61) | MEN1TP53KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116763-A1 | PYRIDAZINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海优理惠生医药有限公司 | 2023-06-29 | — | — | WO | disclosed |