Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.58 |
| ▸ | TK1 | P04183 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040039 | 1.00 | TYMS (0.60) | TYMSPOLBRNASE1TK1 | |
| SCHEMBL5709916 | 0.93 | POLB (0.57) | POLBRNASE1TK1 | |
| SCHEMBL9321645 | 0.93 | POLB (0.57) | POLBRNASE1TK1 | |
| SCHEMBL9012072 | 0.93 | POLB (0.57) | POLBRNASE1TK1 | |
| SCHEMBL9321729 | 0.93 | POLB (0.57) | POLBRNASE1TK1 | |
| SCHEMBL4731694 | 0.93 | RNASE1 (0.67) | POLBRNASE1TK1 | |
| SCHEMBL21886800 | 0.93 | RNASE1 (0.67) | POLBRNASE1TK1 | |
| SCHEMBL21886792 | 0.93 | RNASE1 (0.67) | POLBRNASE1TK1 | |
| SCHEMBL4731692 | 0.93 | RNASE1 (0.67) | POLBRNASE1TK1 | |
| SCHEMBL7040500 | 0.90 | TYMS (0.60) | TYMSPOLBRNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053212-B1 | Non-standard nucleoside analogs with reduced epimerization | BENNER STEVEN ALBERT | 2011-11-08 | — | — | US | disclosed |