Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810418 | 0.86 | EPHX2 (0.43) | LMNAMAPK1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL25840973 | 0.83 | CNR2 (0.45) | LMNAMAPK1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL24597133 | 0.82 | CHRM4 (0.36) | LMNAMAPK1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL25810394 | 0.82 | HPGD (0.56) | LMNAMAPK1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL25810405 | 0.81 | TSHR (0.49) | LMNAMAPK1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL17809474 | 0.78 | ALDH1A1 (0.57) | LMNAALDH1A1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL25810399 | 0.78 | ALDH1A1 (0.63) | LMNAALDH1A1NPSR1TSHRSMN1; SMN2 | |
| SCHEMBL17176113 | 0.78 | PIK3R1 (0.45) | LMNAMAPK1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL17176111 | 0.78 | PIK3R1 (0.45) | LMNAMAPK1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL26615179 | 0.77 | HPGD (0.60) | LMNAMAPK1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116763-A1 | PYRIDAZINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海优理惠生医药有限公司 | 2023-06-29 | — | — | WO | disclosed |