Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810418 | 0.90 | EPHX2 (0.43) | CNR2EPHX2ALDH1A1TSHRMAPK1 | |
| SCHEMBL25843141 | 0.83 | LMNA (0.38) | ALDH1A1CYP2C19TSHRMAPK1HSD11B1 | |
| SCHEMBL17176113 | 0.83 | PIK3R1 (0.45) | CNR2EPHX2ALDH1A1MAPK1HSD11B1 | |
| SCHEMBL17176111 | 0.83 | PIK3R1 (0.45) | CNR2EPHX2ALDH1A1MAPK1HSD11B1 | |
| SCHEMBL17809474 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD11B1LMNAL3MBTL1 | |
| SCHEMBL25810399 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD11B1LMNANPSR1 | |
| SCHEMBL17546315 | 0.81 | EPHX2 (0.46) | CNR2EPHX2ALDH1A1TSHRMAPK1 | |
| SCHEMBL25810405 | 0.80 | TSHR (0.49) | ALDH1A1TSHRMAPK1LMNAL3MBTL1 | |
| SCHEMBL25840964 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHSD11B1LMNANPSR1 | |
| SCHEMBL25810394 | 0.77 | HPGD (0.56) | ALDH1A1TSHRMAPK1HSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116763-A1 | PYRIDAZINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海优理惠生医药有限公司 | 2023-06-29 | — | — | WO | disclosed |