Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706462 | 0.92 | SLC18A3 (0.44) | GNAO1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8054785 | 0.86 | CHRM2 (0.46) | GNAO1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13827095 | 0.85 | GNAO1 (0.50) | GNAO1GNAI3GNAI1CHRM2CHRM4 | |
| SCHEMBL1098014 | 0.84 | NCF1 (0.48) | NCF1GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL245769 | 0.83 | NCF1 (0.56) | NCF1GNAO1GNAI3GNAI1ACHE | |
| SCHEMBL19033278 | 0.82 | GNAO1 (0.50) | NCF1GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL1626971 | 0.82 | NCF1 (0.46) | NCF1GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL5652679 | 0.81 | GNAO1 (0.55) | GNAO1GNAI3GNAI1CHRM2CHRM4 | |
| SCHEMBL1318049 | 0.81 | SLC18A3 (0.46) | GNAO1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18689493 | 0.80 | CARM1 (0.47) | GNAO1GNAI3GNAI1SLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107648-A2 | SYNTHESIS OF ESTER, CARBONATE, AND CARBAMATE-DERIVED NOVEL BIODEGRADABLE IONIZABLE LIPIDS FROM METHYL RICINOLEATE OR METHYL 12-HYDROXYSTEARATE AND ITS APPLICATIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-15 | — | — | WO | disclosed |