Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | STK10 | O94804 | 1/20 | 0.32 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25844447 | 0.97 | ALK (0.34) | ALKSTK10SLKHIF1APIK3CA | |
| SCHEMBL25844458 | 0.96 | PIK3CA (0.32) | ALKSTK10SLKPIK3CAMAPT | |
| SCHEMBL25844449 | 0.94 | MAPT (0.35) | ALKHIF1APIK3CALCKMAPT | |
| SCHEMBL25844452 | 0.92 | ALK (0.33) | ALKHIF1APIK3CAMAPTALDH1A1 | |
| SCHEMBL25844442 | 0.92 | ALDH1A1 (0.33) | ALKMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29453309 | 0.92 | STK10 (0.35) | STK10SLKHIF1APIK3CAMAPT | |
| SCHEMBL1045266 | 0.92 | STK10 (0.35) | STK10SLKHIF1APIK3CAMAPT | |
| SCHEMBL3707410 | 0.92 | HIF1A (0.34) | STK10SLKHIF1APIK3CAMAPT | |
| SCHEMBL25844698 | 0.91 | MAPT (0.34) | ALKMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL25844445 | 0.90 | MAPT (0.33) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227717-A1 | PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-07-20 | — | — | US | disclosed |