Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25844458 | 0.97 | PIK3CA (0.32) | ALKPIK3CAALDH1A1MAPTPKM | |
| SCHEMBL25844455 | 0.97 | ALDH1A1 (0.33) | ALKPIK3CAALDH1A1MAPTHTT | |
| SCHEMBL25844447 | 0.95 | ALK (0.34) | ALKPIK3CATGFBR1ACVR1HIF1A | |
| SCHEMBL15763099 | 0.95 | PRKDC (0.32) | ALDH1A1MAPTPKMHTTNPSR1 | |
| SCHEMBL25844442 | 0.94 | ALDH1A1 (0.33) | ALKALDH1A1MAPTPKMHTT | |
| SCHEMBL25844449 | 0.92 | MAPT (0.35) | ALKPIK3CAHIF1AALDH1A1MAPT | |
| SCHEMBL25844451 | 0.92 | ALK (0.33) | ALKPIK3CATGFBR1ACVR1HIF1A | |
| SCHEMBL25844445 | 0.92 | MAPT (0.33) | ALDH1A1MAPTPKMHTTNPSR1 | |
| SCHEMBL25844425 | 0.91 | STK10 (0.35) | PIK3CAHIF1AALDH1A1MAPTNPSR1 | |
| SCHEMBL25716497 | 0.90 | TNIK (0.37) | ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227717-A1 | PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-07-20 | — | — | US | disclosed |