SCHEMBL25844814

SCHEMBL25844814

CC(I)C(=O)Oc1ccc(OC(=O)C(F)(F)S(=O)(=O)O)c(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 5/20 0.33
RORC P51449 2/20 0.33
EPAS1 Q99814 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
PPARA Q07869 5/20 0.32
FFAR1 O14842 1/20 0.32
CA2 P00918 1/20 0.32
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32
KCNH2 Q12809 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.31
PPARD Q03181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25845012 0.88 EPAS1 (0.35) SCN9ARORCEPAS1PPARAFFAR1
SCHEMBL25844818 0.87 CA2 (0.32) CA2
SCHEMBL25844801 0.87 CA2 (0.32) CA2
SCHEMBL25844808 0.86 CA2 (0.34) EPAS1CA2
SCHEMBL25844798 0.84 ELANE (0.40)
SCHEMBL25844824 0.82 ALDH3A1 (0.39) EPAS1
SCHEMBL25844811 0.81 CA2 (0.33) EPAS1CA2
SCHEMBL25844815 0.81
SCHEMBL25844803 0.78
SCHEMBL25844820 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11709426-B2 Resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-25 US disclosed