Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397508 | 0.85 | ALDH1A1 (0.55) | CNR2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5509730 | 0.83 | POLB (0.54) | CNR2BLMPMP22HIF1AMAPT | |
| SCHEMBL12987195 | 0.82 | FAAH (0.51) | BLMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17663690 | 0.81 | HDAC1 (0.56) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL13753623 | 0.80 | KDM4E (0.51) | BLMMAPTKMT2AHTTKDM4E | |
| SCHEMBL17033016 | 0.79 | ALDH1A1 (0.53) | MPOCYP3A4MAPTALDH1A1MAOA | |
| SCHEMBL5509522 | 0.79 | CACNA1B (0.56) | CYP3A4BLMHIF1AMAPTALDH1A1 | |
| SCHEMBL5513628 | 0.79 | MAPK1 (0.53) | MAPTALDH1A1MEN1KMT2ACA1 | |
| SCHEMBL2961563 | 0.77 | CNR2 (0.47) | CNR2GFERMAPTMEN1KMT2A | |
| SCHEMBL4309743 | 0.77 | MEN1 (0.54) | CNR2ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122212-A2 | SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SOUTHERN RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |