SCHEMBL258453

SCHEMBL258453

CCC(C)c1ccccc1OP(=O)(Oc1ccccc1C(C)CC)Sc1ccccc1C(C)CC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.41
KDM4E B2RXH2 2/20 0.41
NISCH Q9Y2I1 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
ATM Q13315 1/20 0.38
LMNA P02545 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ELANE P08246 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8653646 0.89 KDM4E (0.40) L3MBTL1KDM4ENISCHTSHRHTT
SCHEMBL258293 0.82 KMT2A (0.37) L3MBTL1NISCHTSHRLMNAALDH1A1
SCHEMBL1789705 0.80 TSHR (0.48) L3MBTL1KDM4ENISCHTSHRHTT
SCHEMBL11784190 0.76 TSHR (0.36) TSHR
SCHEMBL8019074 0.74 TSHR (0.46) L3MBTL1KDM4ENISCHTSHRHTT
SCHEMBL11570315 0.74 TSHR (0.42) L3MBTL1KDM4ENISCHTSHRHTT
SCHEMBL11568518 0.74 TSHR (0.42) L3MBTL1KDM4ENISCHTSHRHTT
SCHEMBL29830078 0.73 TSHR (0.48) L3MBTL1KDM4ENISCHTSHRHTT
SCHEMBL258454 0.73 TSHR (0.48) L3MBTL1KDM4ENISCHTSHRHTT
SCHEMBL11068414 0.73 ANPEP (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11946012-B2 Lubricating oil composition SHELL USA, INC. (US) 2024-04-02 US disclosed
US-20230002695-A1 LUBRICATING OIL COMPOSITION SHELL USA, INC. 2023-01-05 US disclosed
US-11254890-B2 Lubricant composition TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-02-22 US disclosed
WO-2021079976-A1 LUBRICATING OIL COMPOSITION FOR AUTOMOTIVE GEARS SHELL LUBRICANTS JAPAN K.K. (JP) 2021-04-29 WO disclosed
US-20210054299-A1 LUBRICANT COMPOSITION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2021-02-25 US disclosed
EP-2980194-B1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2020-04-01 EP disclosed
EP-2855645-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2019-08-14 EP disclosed
EP-2104728-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2018-10-24 EP disclosed
US-9410106-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2016-08-09 US disclosed
EP-2980194-A1 LUBRICANT OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2016-02-03 EP disclosed
US-20080026963-A1 Grease composition for one-way clutch NIPPON OIL CORPORATION (JP) 2008-01-31 US disclosed
WO-2008009704-A1 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2008-01-24 WO disclosed
EP-1867705-A1 GREASE COMPOSITION FOR ONE-WAY CLUTCH Nippon Oil Corporation (JP) 2007-12-19 EP disclosed
EP-1832647-A1 OIL COMPOSITION FOR USE IN TRACE OIL SUPPLY CUTTING / GRINDING WORK Nippon Oil Corporation (JP) 2007-09-12 EP disclosed
US-20070191240-A1 METAL WORKING FLUID NIPPON OIL CORPORATION (JP) 2007-08-16 US disclosed
US-20070179066-A1 Grease composition for constant velocity joint NIPPON OIL CORPORATION (JP) 2007-08-02 US disclosed
US-20070032391-A1 Refrigerating machine oil composition NIPPON OIL CORPORATION (JP) 2007-02-08 US disclosed
EP-1741771-A1 METALWORKING FLUID Nippon Oil Corporation (JP) 2007-01-10 EP disclosed
EP-1721957-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT Nippon Oil Corporation (JP) 2006-11-15 EP disclosed
EP-1702972-A1 METALWORKING FLUID Nippon Oil Corporation (JP) 2006-09-20 EP disclosed