Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29830078 | 0.86 | TSHR (0.48) | TSHRKDM4EL3MBTL1ATMNISCH | |
| SCHEMBL258454 | 0.86 | TSHR (0.48) | TSHRKDM4EL3MBTL1ATMNISCH | |
| SCHEMBL8019081 | 0.84 | TSHR (0.43) | TSHRKDM4EL3MBTL1ATMNISCH | |
| SCHEMBL28495756 | 0.83 | TSHR (0.50) | TSHRKDM4EL3MBTL1ATMNISCH | |
| SCHEMBL8016123 | 0.82 | GABRA1 (0.38) | TSHRL3MBTL1NISCHALDH1A1LMNA | |
| SCHEMBL1789705 | 0.79 | TSHR (0.48) | TSHRKDM4EL3MBTL1ATMNISCH | |
| SCHEMBL5850344 | 0.77 | LMNA (0.33) | TSHRLMNA | |
| SCHEMBL19355318 | 0.76 | TSHR (0.57) | TSHRKDM4EL3MBTL1ATMNISCH | |
| SCHEMBL29657286 | 0.76 | TSHR (0.57) | TSHRKDM4EL3MBTL1ATMNISCH | |
| SCHEMBL19314294 | 0.76 | TSHR (0.57) | TSHRKDM4EL3MBTL1ATMNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573182-B1 | Process for extracting metal values | AVECIA LTD (GB) | 2000-01-05 | — | — | EP | disclosed |
| US-5728853-A | AMIDO(BISTHIOPHOSHORYL) COMPOUNDS USEFUL FOR EXTRACTING METAL VALUES FROM AQUEOUS SOLUTIONS OF METAL SALTS | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| US-5557003-A | SOLVENT EXTRACTION OF ZINC FROM ORE | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |
| US-5502250-A | HYDROMETALLURGICAL PROCESS FOR EXTRACTING ZINC FROM ORE | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |
| US-5433855-A | Solvent extraction | ZENECA LIMITED (GB) | 1995-07-18 | — | — | US | disclosed |
| US-5393431-A | Solvent extraction using a aminobis(thiophosphoryl) compound | ZENECA LIMITED (GB) | 1995-02-28 | — | — | US | disclosed |
| EP-0573182-A1 | Process for extracting metal values | ZENECA LIMITED (GB) | 1993-12-08 | — | — | EP | disclosed |