SCHEMBL258293

SCHEMBL258293

CC(C)c1ccccc1OP(=O)(Oc1ccccc1C(C)C)Sc1ccccc1C(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
NISCH Q9Y2I1 2/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
LMNA P02545 4/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
KCNK3 O14649 1/20 0.34
KCNK9 Q9NPC2 1/20 0.34
P2RX3 P56373 1/20 0.33
P2RX2 Q9UBL9 1/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 3/20 0.33
PLA2G1B P04054 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8016116 0.88 KMT2A (0.35) KMT2AMEN1NISCHADRA2AADRA2B
SCHEMBL258453 0.82 L3MBTL1 (0.41) KMT2ANISCHLMNAL3MBTL1ALDH1A1
SCHEMBL222948 0.78 LMNA (0.38) KMT2AMEN1NISCHADRA2AADRA2B
SCHEMBL220984 0.78 LMNA (0.38) KMT2AMEN1NISCHADRA2AADRA2B
SCHEMBL29352226 0.77 KMT2A (0.40) KMT2AMEN1NISCHADRA2AADRA2B
SCHEMBL18252 0.77 KMT2A (0.40) KMT2AMEN1NISCHADRA2AADRA2B
SCHEMBL222949 0.75 KMT2A (0.37) KMT2AMEN1NISCHADRA2AADRA2B
SCHEMBL220985 0.75 KMT2A (0.37) KMT2AMEN1NISCHADRA2AADRA2B
SCHEMBL224271 0.74 INPPL1 (0.52) KMT2AMEN1LMNAKCNK3KCNK9
SCHEMBL2475805 0.74 GABRA1 (0.42) KMT2AMEN1LMNAL3MBTL1KCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11946012-B2 Lubricating oil composition SHELL USA, INC. (US) 2024-04-02 US disclosed
US-20230002695-A1 LUBRICATING OIL COMPOSITION SHELL USA, INC. 2023-01-05 US disclosed
US-11254890-B2 Lubricant composition TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-02-22 US disclosed
WO-2021079976-A1 LUBRICATING OIL COMPOSITION FOR AUTOMOTIVE GEARS SHELL LUBRICANTS JAPAN K.K. (JP) 2021-04-29 WO disclosed
US-20210054299-A1 LUBRICANT COMPOSITION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2021-02-25 US disclosed
EP-2980194-B1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2020-04-01 EP disclosed
EP-2855645-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2019-08-14 EP disclosed
EP-2104728-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2018-10-24 EP disclosed
US-9410106-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2016-08-09 US disclosed
EP-2980194-A1 LUBRICANT OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2016-02-03 EP disclosed
US-20080318820-A1 Oil Composition for Use in Trace Oil Supply Cutting/Grinding Work NIPPON OIL CORPORATION (JP) 2008-12-25 US disclosed
US-20080026963-A1 Grease composition for one-way clutch NIPPON OIL CORPORATION (JP) 2008-01-31 US disclosed
EP-1867705-A1 GREASE COMPOSITION FOR ONE-WAY CLUTCH Nippon Oil Corporation (JP) 2007-12-19 EP disclosed
EP-1832647-A1 OIL COMPOSITION FOR USE IN TRACE OIL SUPPLY CUTTING / GRINDING WORK Nippon Oil Corporation (JP) 2007-09-12 EP disclosed
US-20070191240-A1 METAL WORKING FLUID NIPPON OIL CORPORATION (JP) 2007-08-16 US disclosed
US-20070179066-A1 Grease composition for constant velocity joint NIPPON OIL CORPORATION (JP) 2007-08-02 US disclosed
US-20070032391-A1 Refrigerating machine oil composition NIPPON OIL CORPORATION (JP) 2007-02-08 US disclosed
EP-1741771-A1 METALWORKING FLUID Nippon Oil Corporation (JP) 2007-01-10 EP disclosed
EP-1721957-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT Nippon Oil Corporation (JP) 2006-11-15 EP disclosed
EP-1702972-A1 METALWORKING FLUID Nippon Oil Corporation (JP) 2006-09-20 EP disclosed