SCHEMBL25845404

SCHEMBL25845404

C[C@@H]1O[C@H](CO)C[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21859156 1.00 PPM1D (0.32) PPM1D
SCHEMBL25845470 0.82
SCHEMBL27055121 0.77 CHRM5 (0.32)
SCHEMBL16500804 0.73 PPM1D (0.32) PPM1D
SCHEMBL7892350 0.72
SCHEMBL23658927 0.72 PPM1D (0.33) PPM1D
SCHEMBL25798902 0.72 PPM1D (0.33) PPM1D
SCHEMBL12359674 0.70
SCHEMBL16772247 0.69 PPM1D (0.30) PPM1D
SCHEMBL4074631 0.69 CYP2A6 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3730504-B1 CYTARABINE PRODRUG NUCLEOSIDE CYCLIC PHOSPHATE COMPOUND BASED ON LIVER-SPECIFIC DELIVERY AND USE ZHEJIANG PALO ALTO PHARMACEUTICALS INC (CN) 2023-07-12 EP disclosed