⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25845404 | 0.82 | PPM1D (0.32) | — | |
| SCHEMBL21859156 | 0.82 | PPM1D (0.32) | — | |
| SCHEMBL12359673 | 0.72 | — | — | |
| SCHEMBL18520342 | 0.69 | CHRM5 (0.32) | — | |
| SCHEMBL9594350 | 0.69 | PPM1D (0.30) | — | |
| SCHEMBL16772247 | 0.68 | PPM1D (0.30) | — | |
| SCHEMBL17717997 | 0.67 | CHRM5 (0.53) | — | |
| SCHEMBL12359676 | 0.67 | — | — | |
| SCHEMBL6555758 | 0.67 | PPM1D (0.34) | — | |
| SCHEMBL18519935 | 0.66 | CHRM2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3730504-B1 | CYTARABINE PRODRUG NUCLEOSIDE CYCLIC PHOSPHATE COMPOUND BASED ON LIVER-SPECIFIC DELIVERY AND USE | ZHEJIANG PALO ALTO PHARMACEUTICALS INC (CN) | 2023-07-12 | — | — | EP | disclosed |