SCHEMBL258457

SCHEMBL258457

O=C(O)c1cc(C(=O)O)c(C(=O)O)nc1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 4/20 0.43
TSHR P16473 4/20 0.43
ALOX15 P16050 3/20 0.43
MAPT P10636 2/20 0.43
CYP3A4 P08684 1/20 0.43
BLM P54132 1/20 0.43
AGER Q15109 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
ASPH Q12797 2/20 0.40
KDM8 Q8N371 2/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
CYP1A2 P05177 1/20 0.39
HIF1A Q16665 1/20 0.39
IDO1 P14902 1/20 0.37
LCK P06239 1/20 0.36
CA12 O43570 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29110843 0.97 ALDH1A1 (0.41) ALDH1A1KDM4ETSHRALOX15MAPT
SCHEMBL30660932 0.97 ALDH1A1 (0.41) ALDH1A1KDM4ETSHRALOX15MAPT
SCHEMBL3810886 0.87 ALDH1A1 (0.35) ALDH1A1KDM4ETSHRALOX15MAPT
Pyrrole SCHEMBL28313282 0.85 KDM4E (0.38) ALDH1A1KDM4ETSHRALOX15MAPT
SCHEMBL9315436 0.84 SMN1; SMN2 (0.50) ALDH1A1KDM4ESMN1; SMN2LCKCA12
SCHEMBL2805794 0.82 IKBKB (0.39) ALDH1A1KDM4ETSHRALOX15MAPT
SCHEMBL3875708 0.80 ALDH1A1 (0.38) ALDH1A1KDM4ETSHRALOX15MAPT
SCHEMBL30447160 0.79 SMN1; SMN2 (0.50) ALDH1A1KDM4ESMN1; SMN2KEAP1NFE2L2
SCHEMBL2271379 0.79 ALDH1A1 (0.45) ALDH1A1KDM4ETSHRALOX15MAPT
SCHEMBL8591590 0.77 KEAP1 (0.46) ALDH1A1KDM4ETSHRL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118619502-B Method for treating port chemical wastewater 交通运输部天津水运工程科学研究所 2024-10-22 CN claimed
CN-118619502-A Method for treating port chemical wastewater 交通运输部天津水运工程科学研究所 2024-09-10 CN claimed
CN-115926218-B Aromatic imide film 宁波博雅聚力新材料科技有限公司 2024-06-21 CN claimed
CN-115232017-B Compound, resin and preparation method and application thereof 华为技术有限公司 2024-06-18 CN claimed
CN-118047948-A Resin, preparation method thereof and resin composition 华为技术有限公司 2024-05-17 CN claimed
CN-117304037-A Diamine monomer, preparation method thereof, resin and application thereof 华为技术有限公司 2023-12-29 CN claimed
EP-3143067-B1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-09-13 EP claimed
CN-114621437-B Compound for preparing photosensitive resin film, preparation method and application thereof 吉林奥来德光电材料股份有限公司 2023-08-18 CN claimed
CN-115926218-A Aromatic imide film 宁波博雅聚力新材料科技有限公司 2023-04-07 CN claimed
US-20230091989-A1 DIAMINE MONOMER COMPOUND, METHOD FOR PREPARING THE SAME, RESIN, FLEXIBLE FILM, AND ELECTRONIC DEVICE Zhen Ding Technology Co., Ltd. (TW) 2023-03-23 US claimed
WO-1991001340-A1 POLYIMIDES COMPRISING SUBSTITUTED BENZIDINES THE UNIVERSITY OF AKRON (US) 1991-02-07 WO claimed
US-4847358-A HEAT RESISTANT ELECTRONICS HITACHI CHEMICAL COMPANY, LTD. (JP) 1989-07-11 US claimed
US-4758476-A Polyimide precursor resin composition and semiconductor device using the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1988-07-19 US claimed
EP-0260833-A2 Process for producing polyamide acid having siloxane bonds and polyimide having siloxane bonds and isoindoloquinazolinedione rings HITACHI CHEMICAL COMPANY (JP) 1988-03-23 EP claimed
EP-0251828-A1 Insulating resin composition and semiconductor device using the same Hitachi Chemical Co., Ltd. (JP) 1988-01-07 EP claimed
EP-0184937-A2 Polyimide precursor resin composition and semiconductor device using the same Hitachi Chemical Co., Ltd. (JP) 1986-06-18 EP claimed
US-4485234-A FROM DIAMINE, DIANHYDRIDE, AND DIAMINECARBONAMIDE HITACHI CHEMICAL COMPANY, LTD. (JP) 1984-11-27 US claimed
US-4447596-A REACTING DIAMINE AND DIANHYDRIDE AT LOW TEMPERATURE, THEN ADJUSTMENT OF VISCOSITY BY HEATING HITACHI CHEMICAL COMPANY, LTD. (JP) 1984-05-08 US claimed
US-4381886-A HYDRAZIDE-IMIDE COPOLYMER HITACHI, LTD. (JP) 1983-05-03 US claimed
US-4338427-A HEAT, WEAR, AND CHEMICAL RESISTANCE HITACHI CHEMICAL COMPANY LTD. (JP) 1982-07-06 US claimed