Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565510 | 0.87 | RAB9A (0.71) | SMN1; SMN2ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL5637308 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL6002968 | 0.84 | RAB9A (0.59) | SMN1; SMN2ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL10668920 | 0.84 | RAB9A (0.64) | SMN1; SMN2ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL10941324 | 0.84 | NAMPT (0.69) | SMN1; SMN2ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL8132597 | 0.84 | RAB9A (1.00) | SMN1; SMN2ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL11455508 | 0.83 | MAPT (0.67) | SMN1; SMN2ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL15127704 | 0.83 | RAB9A (0.58) | SMN1; SMN2ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL5636399 | 0.83 | RAB9A (0.72) | SMN1; SMN2ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL4129868 | 0.83 | RAB9A (0.58) | SMN1; SMN2ALDH1A1MAPK1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122212-A2 | SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SOUTHERN RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |