Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969552 | 0.85 | KMT2A (0.55) | HDAC3HDAC1HDAC2KMT2AGAA | |
| SCHEMBL30152391 | 0.85 | KMT2A (0.55) | HDAC3HDAC1HDAC2KMT2AGAA | |
| SCHEMBL20460484 | 0.82 | KMT2A (0.74) | HDAC3HDAC1HDAC2KMT2AGAA | |
| SCHEMBL20460483 | 0.82 | KMT2A (0.58) | HDAC3HDAC1HDAC2KMT2AGAA | |
| SCHEMBL25678232 | 0.81 | KMT2A (0.56) | HDAC3HDAC1HDAC2KMT2AGAA | |
| SCHEMBL27178877 | 0.80 | KMT2A (0.49) | HDAC3HDAC1HDAC2KMT2AMEN1 | |
| SCHEMBL27178847 | 0.80 | KMT2A (0.49) | HDAC3HDAC1HDAC2KMT2AMEN1 | |
| SCHEMBL26122265 | 0.80 | KMT2A (0.59) | HDAC3HDAC1HDAC2KMT2AGAA | |
| SCHEMBL32662692 | 0.80 | KMT2A (0.73) | HDAC3HDAC1HDAC2KMT2AGAA | |
| SCHEMBL28587997 | 0.80 | SMN1; SMN2 (0.68) | HDAC3HDAC1HDAC2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | C4 THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | BRD9, BRD1, BRWD1 | HDAC3 1289/4885HDAC1 724/4885HDAC2 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.