Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969552 | 1.00 | KMT2A (0.55) | KMT2AHDAC1HDAC2HDAC3TP53 | |
| SCHEMBL25845880 | 0.85 | HDAC3 (0.60) | KMT2AHDAC1HDAC2HDAC3TP53 | |
| SCHEMBL18508243 | 0.80 | AAK1 (0.59) | KMT2AHDAC1HDAC2HDAC3POLB | |
| SCHEMBL30152223 | 0.80 | KMT2A (0.50) | KMT2ATP53MEN1HTTGAA | |
| SCHEMBL24969054 | 0.78 | KMT2A (0.48) | KMT2AHDAC1HDAC2HDAC3TP53 | |
| SCHEMBL26122265 | 0.77 | KMT2A (0.59) | KMT2AHDAC1HDAC2HDAC3TP53 | |
| SCHEMBL26673872 | 0.75 | GSK3B (0.41) | BACE1 | |
| SCHEMBL27178877 | 0.74 | KMT2A (0.49) | KMT2AHDAC1HDAC2HDAC3TP53 | |
| SCHEMBL27178847 | 0.74 | KMT2A (0.49) | KMT2AHDAC1HDAC2HDAC3TP53 | |
| SCHEMBL23783189 | 0.73 | PTPN2 (0.58) | KMT2AHDAC1HDAC2HDAC3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |