Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13581616 | 0.84 | KMT2A (0.72) | SMN1; SMN2TSHRKDM4EALDH1A1RAB9A | |
| SCHEMBL26154084 | 0.83 | KMT2A (0.69) | SMN1; SMN2TSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL25678232 | 0.82 | KMT2A (0.56) | SMN1; SMN2KDM4ERAB9AKMT2AGAA | |
| SCHEMBL14503304 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2TSHRKDM4EALDH1A1RAB9A | |
| SCHEMBL1749404 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2TSHRKDM4EALDH1A1RAB9A | |
| SCHEMBL25845880 | 0.80 | HDAC3 (0.60) | SMN1; SMN2TSHRRAB9AKMT2AGAA | |
| SCHEMBL28595943 | 0.79 | PKM (0.66) | SMN1; SMN2TSHRALDH1A1KMT2AGAA | |
| SCHEMBL1916986 | 0.78 | KMT2A (0.70) | SMN1; SMN2TSHRKDM4EALDH1A1RAB9A | |
| SCHEMBL2071884 | 0.77 | GAA (0.59) | SMN1; SMN2TSHRALDH1A1RAB9AMAPT | |
| SCHEMBL6353701 | 0.77 | MAPT (0.59) | SMN1; SMN2TSHRALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061098-B | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113061098-A | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-07-02 | — | — | CN | disclosed |