SCHEMBL258467

SCHEMBL258467

CC(O)C(O)c1cnc2c(O)nc(N)nc2n1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.39
PIK3CG P48736 4/20 0.35
APLNR P35414 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8575908 0.98 HSD17B10 (0.39) HSD17B10PIK3CGAPLNR
SCHEMBL1524830 0.94 HSD17B10 (0.36) HSD17B10PIK3CGMEN1ALDH1A1MAPT
SCHEMBL4361085 0.88 HSD17B10 (0.48) HSD17B10PIK3CGAPLNR
SCHEMBL8424661 0.81 HSD17B10 (0.34) HSD17B10
SCHEMBL5508888 0.79 HSD17B10 (0.33) HSD17B10APLNR
SCHEMBL23028961 0.77 HSD17B10 (0.49) HSD17B10PIK3CG
SCHEMBL7761455 0.77 HSD17B10 (0.49) HSD17B10PIK3CG
SCHEMBL2746213 0.75 KDM4E (0.34) HSD17B10
SCHEMBL2745828 0.75 HSD17B10 (0.33) HSD17B10APLNR
SCHEMBL11620601 0.74 PIK3CG (0.41) PIK3CGMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4427 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048056-A1 SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS VASOPHARM GMBH (DE) 2026-02-19 US claimed
US-20250288555-A1 SYSTEMS AND METHODS TO IMPROVE EXERCISE TOLERANCE EPICENTRX, INC. (US) 2025-09-18 US claimed
CN-120142525-A Method for detecting related substances in sapropterin hydrochloride tablet 上海奥科达医药科技股份有限公司 2025-06-13 CN claimed
US-20250120977-A1 METHODS OF TREATING PATIENTS SUFFERING FROM BRAIN INJURY AND METHODS OF INCREASING THE VALUE OF THE EXTENDED GLASGOW OUTCOME SCALE OF PATIENTS SUFFERING FROM BRAIN INJURY VERINOS OPERATIONS GMBH (DE) 2025-04-17 US claimed
EP-4537111-A2 MULTI-OMICS ASSESSMENT Prognomiq Inc (US) 2025-04-16 EP claimed
CN-119816897-A Multiple study assessment 普罗科技有限公司 2025-04-11 CN claimed
WO-2025038846-A1 L-ARGININE FORMULATIONS AND METHODS OF MANAGING PAIN EMORY UNIVERSITY (US) 2025-02-20 WO claimed
US-12171766-B2 Methods of treating patients suffering from brain injury and methods of increasing the value of the extended Glasgow Outcome Scale of patients suffering from brain injury VERINOS OPERATIONS GMBH (DE) 2024-12-24 US claimed
WO-2024212363-A1 USE OF BIOMARKER COMBINATION IN PREPARATION OF BREAST CANCER PREDICTION PRODUCT 南京品生医学检验实验室有限公司 2024-10-17 WO claimed
WO-2024212361-A1 USE OF BIOMARKER COMBINATION IN PREPARATION OF LUNG CANCER PREDICTION PRODUCT 南京品生医学检验实验室有限公司 2024-10-17 WO claimed
US-5043446-A Subjecting ribose to acetalization, Grignard, oxidative cleavage, hydrazoning, condensing with pyridine to 1-biopterin NISSHIN FLOUR MILLING CO., LTD. (JP) 1991-08-27 US claimed
EP-0191335-B1 PREPARATION PROCESS OF (6R)-TETRAHYDRO-L-BIOPTERIN SHIRATORI PHARMACEUTICAL CO. LTD. (JP) 1991-08-14 EP claimed
EP-0385336-A2 Processes for the preparation of pterin derivatives NISSHIN FLOUR MILLING CO., LTD. (JP) 1990-09-05 EP claimed
EP-0318926-A2 Intermediates for synthesizing 5,6,7,8-tetrahydro-L-erythro-biopterin and its derivatives Kabushiki Kaisha Vitamin Kenkyusyo (JP) 1989-06-07 EP claimed
US-4713454-A CATALYTIC HYDROGENATION IN PRESENCE OF AMINE OF ERYTHROBIOPTERIN SHIRATORI PHARMACEUTICAL CO., LTD. (JP) 1987-12-15 US claimed
EP-0079574-B1 PROCESS FOR PREPARING BIOPTERIN AND ITS DERIVATIVES KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-03-04 EP claimed
EP-0164964-A1 Lipoidal biopterin compounds BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1985-12-18 EP claimed
US-4550109-A PHENYLKETONURIA, PARKINSON'S DISEASE, DEPRESSION, SENILE DEMENTIA,ALZHEIMER'S DISEASE THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1985-10-29 US claimed
EP-0156330-A2 Sulfate of 5,6,7,8-tetrahydro-l-erythro-biopterin and process for preparing the same KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-10-02 EP claimed
EP-0012444-B1 DIAGNOSTIC METHOD, ESPECIALLY FOR THE EARLY RECOGNITION OF MALIGNANT TUMORS AND/OR VIRAL DISEASES, AND MEANS TO CARRY IT OUT Wachter, Helmut, Univ.-Prof. Dr. (AT) 1984-07-25 EP claimed