Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258467 | 0.88 | HSD17B10 (0.39) | HSD17B10PIK3CGAPLNR | |
| Hydrochloric Acid SCHEMBL8575908 | 0.87 | HSD17B10 (0.39) | HSD17B10PIK3CGAPLNR | |
| SCHEMBL23028961 | 0.86 | HSD17B10 (0.49) | HSD17B10PIK3CGPIK3CAPIK3CBHDAC6 | |
| SCHEMBL7761455 | 0.86 | HSD17B10 (0.49) | HSD17B10PIK3CGPIK3CAPIK3CBHDAC6 | |
| SCHEMBL25899100 | 0.86 | HSD17B10 (0.39) | HSD17B10PIK3CGPIK3CAPIK3CBHDAC6 | |
| SCHEMBL1524830 | 0.83 | HSD17B10 (0.36) | HSD17B10PIK3CG | |
| SCHEMBL11301495 | 0.82 | HSD17B10 (0.38) | HSD17B10PIK3CGPIK3CAPIK3CBHDAC6 | |
| SCHEMBL5608021 | 0.81 | HSD17B10 (0.45) | HSD17B10PIK3CAAPLNRNOS1 | |
| SCHEMBL9201051 | 0.79 | HSD17B10 (0.38) | HSD17B10PIK3CGPIK3CAPIK3CBHDAC6 | |
| SCHEMBL11628253 | 0.79 | PIK3CG (0.35) | HSD17B10PIK3CGPIK3CAPIK3CBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56099484-A | — | — | None | — | — | JP | disclosed |
| US-20090286802-A1 | High Dose Folic Acid Compositions for Vascular Dysfunction | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-11-19 | — | — | US | disclosed |
| EP-1874386-A1 | HIGH DOSE FOLIC ACID COMPOSITIONS FOR VASCULAR DYSFUNCTION | THE GENERAL HOSPITAL CORPORATION (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006113389-A1 | HIGH DOSE FOLIC ACID COMPOSITIONS FOR VASCULAR DYSFUNCTION | THE GENERAL HOSPITAL CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |
| JP-2005015417-A | ANTIFATIGUE COMPOSITION | SOGO IKAGAKU KENKYUSHO:KK | 2005-01-20 | — | — | JP | disclosed |
| EP-0370960-A1 | Neopterin as a marker in a diagnostic screening test kit to detect retrovirus diseases | Pera, Ivo E. (US) | 1990-05-30 | — | — | EP | disclosed |
| US-4371514-A | Radioimmunoassay of pterins and novel pterin derivatives useful therefor | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 1983-02-01 | — | — | US | disclosed |
| JP-S5699484-A | PTERIN DERIVATIVE AND DETERMINATION OF PTERINS | DAIICHI RAJIO ISOTOPE KENKYUSHO:KK | 1981-08-10 | — | — | JP | disclosed |