Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2746213 | 0.77 | KDM4E (0.34) | HSD17B10 | |
| Hydrochloric Acid SCHEMBL8575908 | 0.74 | HSD17B10 (0.39) | HSD17B10APLNR | |
| SCHEMBL30515237 | 0.64 | HSD17B10 (0.68) | HSD17B10 | |
| SCHEMBL4365313 | 0.60 | KMT2A (0.41) | HSD17B10 | |
| SCHEMBL15952738 | 0.58 | KDM4E (0.38) | HSD17B10 | |
| SCHEMBL23028961 | 0.57 | HSD17B10 (0.49) | HSD17B10 | |
| SCHEMBL13947293 | 0.56 | HSD17B10 (0.85) | HSD17B10 | |
| SCHEMBL258468 | 0.56 | HSD17B10 (0.85) | HSD17B10 | |
| SCHEMBL29776986 | 0.56 | HSD17B10 (0.85) | HSD17B10 | |
| SCHEMBL29400382 | 0.56 | HSD17B10 (0.85) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872293-A | Chemical synthesis and purification method of biopterin | 北京启慧生物医药有限公司 | 2020-03-10 | — | — | CN | claimed |
| WO-2016189542-A1 | NOVEL PROCESS FOR THE PREPARATION OF SAPROPTERIN DIHYDROCHLORIDE AND ITS KEY INTERMEDIATE, L-BIOPTERIN | NATCO PHARMA LTD (IN) | 2016-12-01 | — | — | WO | claimed |
| US-8178670-B2 | Method of synthesizing tetrahydrobiopterin | BIOMARIN PHARMACEUTICAL INC. (US) | 2012-05-15 | — | — | US | claimed |
| EP-2240484-A1 | METHOD OF SYNTHESIZING TETRAHYDROBIOPTERIN | BioMarin Pharmaceutical Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| US-20090198055-A1 | METHOD OF SYNTHESIZING TETRAHYDROBIOPTERIN | BIOMARIN PHARMACEUTICAL INC. (US) | 2009-08-06 | — | — | US | claimed |
| WO-2009088979-A1 | METHOD OF SYNTHESIZING TETRAHYDROBIOPTERIN | BIOMARIN PHARMACEUTICAL INC. (US) | 2009-07-16 | — | — | WO | claimed |
| US-5043446-A | Subjecting ribose to acetalization, Grignard, oxidative cleavage, hydrazoning, condensing with pyridine to 1-biopterin | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| US-12605386-B2 | Sapropterin formulation | APR APPLIED PHARMA RESEARCH SA (CH) | 2026-04-21 | — | — | US | disclosed |
| US-20250339439-A1 | Sapropterin Formulation | APR APPLIED PHARMA RESEARCH SA (CH) | 2025-11-06 | — | — | US | disclosed |
| CN-118984698-A | Sapropterin formulations | APR应用制药研究股份有限公司 | 2024-11-19 | — | — | CN | disclosed |
| WO-2023148662-A1 | SAPROPTERIN FORMULATION | APR APPLIED PHARMA RESEARCH S.A. (CH) | 2023-08-10 | — | — | WO | disclosed |
| US-20230241069-A1 | Sapropterin Formulation | APR APPLIED PHARMA RESEARCH SA (CH) | 2023-08-03 | — | — | US | disclosed |
| CN-110872293-A | Chemical synthesis and purification method of biopterin | 北京启慧生物医药有限公司 | 2020-03-10 | — | — | CN | disclosed |
| US-5043446-A | Subjecting ribose to acetalization, Grignard, oxidative cleavage, hydrazoning, condensing with pyridine to 1-biopterin | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0385336-A2 | Processes for the preparation of pterin derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |
| EP-0079574-B1 | PROCESS FOR PREPARING BIOPTERIN AND ITS DERIVATIVES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-03-04 | — | — | EP | disclosed |
| EP-0164964-A1 | Lipoidal biopterin compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4550109-A | PHENYLKETONURIA, PARKINSON'S DISEASE, DEPRESSION, SENILE DEMENTIA,ALZHEIMER'S DISEASE | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1985-10-29 | — | — | US | disclosed |
| US-4540783-A | 1',2'-Diacyl-(6R,S)-5,6,7,8-tetrahydro-L-biopterin and process for preparing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0079574-A1 | Process for preparing biopterin and its derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250339439-A1 | Sapropterin Formulation | PSAP, CYP46A1, HSD11B2 | HSD17B10 154/4885APLNR 651/4885 |
| US-20090198055-A1 | METHOD OF SYNTHESIZING TETRAHYDROBIOPTERIN | SPR, THOP1, PTMA | HSD17B10 854/4885APLNR 199/4885 |
| US-20230241069-A1 | Sapropterin Formulation | PSAP, CYP46A1, HSD11B2 | HSD17B10 154/4885APLNR 651/4885 |
| US-12605386-B2 | Sapropterin formulation | PAH, CYP46A1, CYP21A2 | HSD17B10 11/4885APLNR 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.