Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25850418 | 0.75 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL25851587 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL25853945 | 0.74 | GRM5 (0.37) | — | |
| SCHEMBL25850175 | 0.73 | PRMT5 (0.32) | PRMT5 | |
| SCHEMBL25853967 | 0.73 | VNN1 (0.31) | VNN1 | |
| SCHEMBL25853250 | 0.72 | GRM5 (0.39) | — | |
| SCHEMBL28132587 | 0.72 | CA12 (0.58) | CA12CA1CA2CA9PRMT5 | |
| SCHEMBL27904296 | 0.72 | CA12 (0.58) | CA12CA1CA2CA9PRMT5 | |
| SCHEMBL25847383 | 0.71 | — | — | |
| SCHEMBL25848798 | 0.71 | NOTUM (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |