Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 7/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2588671 | 0.94 | KMT2A (0.49) | KMT2AGRM2OPRM1OPRD1OPRK1 | |
| SCHEMBL29173888 | 0.81 | KMT2A (0.46) | KMT2AGRM2OPRM1OPRD1OPRK1 | |
| SCHEMBL287558 | 0.79 | P4HTM (0.53) | KMT2AALOX15GFERADAM17ALDH1A1 | |
| SCHEMBL17668487 | 0.78 | LMNA (0.42) | KMT2ABACE1ALOX15GFERADAM17 | |
| SCHEMBL17963167 | 0.78 | PARP10 (0.56) | KMT2AOPRM1OPRD1OPRK1APP | |
| Formic Acid SCHEMBL2593345 | 0.77 | KMT2A (0.53) | KMT2AOPRM1OPRD1OPRK1BACE1 | |
| Hydrochloric Acid SCHEMBL18035982 | 0.76 | PRMT1 (0.38) | GRM2BACE1ALOX15GFERADAM17 | |
| SCHEMBL2108310 | 0.75 | MAPK1 (0.56) | KMT2ABACE1ALOX15GFERADAM17 | |
| SCHEMBL30640076 | 0.75 | MAPK1 (0.56) | KMT2ABACE1ALOX15GFERADAM17 | |
| SCHEMBL7709287 | 0.74 | ABL1 (0.39) | KMT2ABACE1ALOX15GFERADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138293-A1 | 2,5,6,7-TETRAHYDRO-[1,4]OXAZEPIN-3-YLAMINE OR 2,3,6,7-TETRAHYDRO-[1,4]OXAZEPIN-5-YLAMINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-11-10 | — | — | WO | claimed |