Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15994885 | 0.94 | KMT2A (0.58) | KMT2AOPRM1OPRD1OPRK1CACNA1G | |
| SCHEMBL287075 | 0.80 | P4HTM (0.58) | KMT2ACACNA1GCACNA1HCACNA1ICNR2 | |
| SCHEMBL29601148 | 0.79 | CACNA1I (0.45) | KMT2ACACNA1GCACNA1HCACNA1ICNR2 | |
| SCHEMBL27039792 | 0.79 | CACNA1I (0.45) | KMT2ACACNA1GCACNA1HCACNA1ICNR2 | |
| SCHEMBL21078924 | 0.78 | CACNA1G (0.42) | KMT2ACACNA1GCACNA1HCACNA1ICNR2 | |
| SCHEMBL19309297 | 0.77 | KMT2A (0.50) | KMT2AOPRM1OPRD1OPRK1BACE1 | |
| SCHEMBL17394948 | 0.77 | NPSR1 (0.38) | KMT2ACACNA1GCACNA1HCACNA1ICNR2 | |
| Formic Acid SCHEMBL2584800 | 0.77 | KMT2A (0.44) | KMT2AOPRM1OPRD1OPRK1BACE1 | |
| SCHEMBL14480227 | 0.77 | CACNA1I (0.41) | KMT2ACACNA1GCACNA1HCACNA1ICNR2 | |
| SCHEMBL27039858 | 0.77 | CACNA1G (0.41) | KMT2ACACNA1GCACNA1HCACNA1ICNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138293-A1 | 2,5,6,7-TETRAHYDRO-[1,4]OXAZEPIN-3-YLAMINE OR 2,3,6,7-TETRAHYDRO-[1,4]OXAZEPIN-5-YLAMINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-11-10 | — | — | WO | disclosed |