Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.44 |
| ▸ | CHKA | P35790 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15836459 | 0.79 | ALDH1A1 (0.49) | LMNAACHECHKAALDH1A1HTT | |
| SCHEMBL31652036 | 0.77 | ACHE (0.48) | LMNAACHECHKAALDH1A1HTT | |
| Bromide SCHEMBL15821503 | 0.77 | ACHE (0.50) | LMNAACHECHKAALDH1A1HTT | |
| Bromide SCHEMBL23858158 | 0.74 | CHKA (0.49) | LMNAACHECHKAALDH1A1HTT | |
| SCHEMBL10692064 | 0.72 | CHKA (0.57) | LMNAACHECHKAALDH1A1HTT | |
| SCHEMBL14211654 | 0.72 | ACHE (0.45) | LMNAACHECHKAALDH1A1HTT | |
| SCHEMBL13089694 | 0.71 | ACHE (0.53) | LMNAACHECHKAALDH1A1HTT | |
| Bromide SCHEMBL17632298 | 0.71 | ACHE (0.48) | LMNAACHECHKAALDH1A1HTT | |
| Bromide SCHEMBL9691766 | 0.71 | CHKA (0.58) | LMNAACHECHKAALDH1A1HTT | |
| SCHEMBL1127774 | 0.69 | ACHE (0.85) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133543-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2023-07-13 | — | — | WO | disclosed |