Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | QDPR | P09417 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900834 | 0.80 | QDPR (0.45) | NAMPTHRH3MEN1KMT2ANPC1 | |
| SCHEMBL21840081 | 0.80 | ALDH1A1 (0.36) | KCNH2HRH3MEN1KMT2ANPC1 | |
| SCHEMBL21252975 | 0.79 | GRM1 (0.43) | NAMPTMEN1KMT2A | |
| SCHEMBL20458849 | 0.79 | NAMPT (0.41) | NAMPTKCNH2HRH3NPC1TSHR | |
| SCHEMBL12566963 | 0.78 | PDK4 (0.48) | NAMPTSMN1; SMN2PDK4 | |
| SCHEMBL12142171 | 0.78 | BLM (0.40) | NAMPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8117386 | 0.75 | MAPT (0.43) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL25628761 | 0.75 | MEN1 (0.37) | NAMPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL19454525 | 0.75 | MAPT (0.38) | KCNH2HRH3MEN1KMT2ANPC1 | |
| SCHEMBL19454551 | 0.75 | GRM5 (0.40) | KCNH2HRH3HRH2HRH1PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |