Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25851654 | 0.85 | PDK2 (0.46) | PDK2 | |
| SCHEMBL25849676 | 0.81 | RIPK1 (0.32) | NAMPTFASNRIPK1 | |
| SCHEMBL25848798 | 0.80 | NOTUM (0.42) | — | |
| SCHEMBL25848587 | 0.73 | RIPK1 (0.35) | NAMPTFASNRIPK1PDK2HDAC8 | |
| SCHEMBL25842594 | 0.73 | CGAS (0.39) | NAMPT | |
| SCHEMBL25853945 | 0.72 | GRM5 (0.37) | — | |
| SCHEMBL25850418 | 0.71 | PRMT5 (0.32) | — | |
| SCHEMBL25848915 | 0.71 | NPSR1 (0.30) | — | |
| SCHEMBL25853250 | 0.70 | GRM5 (0.39) | NAMPT | |
| SCHEMBL25851541 | 0.70 | HPGD (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |