Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25843661 | 0.87 | PDK2 (0.44) | — | |
| SCHEMBL25848676 | 0.81 | NAMPT (0.33) | RIPK1NAMPTFASN | |
| SCHEMBL25848587 | 0.76 | RIPK1 (0.35) | RIPK1NAMPTFASN | |
| SCHEMBL25848914 | 0.73 | NAMPT (0.30) | NAMPT | |
| SCHEMBL25850431 | 0.69 | ALOX5AP (0.30) | — | |
| SCHEMBL25853377 | 0.69 | RIPK1 (0.32) | RIPK1NAMPTFASN | |
| SCHEMBL25851654 | 0.68 | PDK2 (0.46) | — | |
| SCHEMBL25848673 | 0.64 | NAMPT (0.43) | RIPK1NAMPTFASN | |
| SCHEMBL22519660 | 0.62 | — | — | |
| SCHEMBL25848798 | 0.61 | NOTUM (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |