Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TERT | O14746 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25017242 | 0.86 | RAB9A (0.68) | SMN1; SMN2HPGDRAB9ANPC1KIF11 | |
| SCHEMBL5440304 | 0.85 | TSHR (0.73) | SMN1; SMN2HPGDRAB9ANPC1KIF11 | |
| SCHEMBL6287639 | 0.85 | CA1 (0.58) | SMN1; SMN2HPGDRAB9ANPC1CA1 | |
| SCHEMBL12545584 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDRAB9ANPC1KIF11 | |
| SCHEMBL104611 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDRAB9ANPC1KIF11 | |
| SCHEMBL23483368 | 0.83 | RAB9A (0.60) | SMN1; SMN2HPGDRAB9ANPC1KIF11 | |
| SCHEMBL12018050 | 0.81 | PTPN1 (0.73) | SMN1; SMN2HPGDRAB9ANPC1KIF11 | |
| SCHEMBL5324688 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDRAB9ANPC1KIF11 | |
| SCHEMBL11193183 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDRAB9ANPC1KIF11 | |
| SCHEMBL11207364 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDRAB9ANPC1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793990-B1 | ANTIBACTERIAL COMPOUNDS | INFEX THERAPEUTICS LTD (GB) | 2023-07-19 | — | — | EP | disclosed |