Sugi Predict

Sugi Predict / Compounds / SCHEMBL5324688

SCHEMBL5324688

SCHEMBL5324688

CC(C)c1ccc(NC(=O)CCl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 5/20 0.65
▸ HPGD P15428 1/20 0.65
▸ RAB9A P51151 8/20 0.60
▸ NPC1 O15118 5/20 0.60
▸ ALDH1A1 P00352 3/20 0.60
▸ HTT P42858 3/20 0.60
▸ KMT2A Q03164 3/20 0.60
▸ LMNA P02545 2/20 0.60
▸ MAPT P10636 2/20 0.60
▸ MITF O75030 2/20 0.58
▸ XBP1 P17861 1/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.58
▸ NOD2 Q9HC29 1/20 0.58
▸ PRMT1 Q99873 1/20 0.56
▸ KIF11 P52732 1/20 0.54
▸ EPHX1 P07099 2/20 0.53
▸ EGFR P00533 1/20 0.52
▸ ERBB2 P04626 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ MEN1 O00255 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9798133 0.85 NPC1 (0.61) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1
SCHEMBL9081388 0.84 NPC1 (0.76) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1
SCHEMBL12545584 0.83 SMN1; SMN2 (0.67) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1
SCHEMBL104611 0.83 SMN1; SMN2 (0.67) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1
SCHEMBL31136175 0.82 SMN1; SMN2 (0.61) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1
SCHEMBL11207364 0.81 SMN1; SMN2 (0.65) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1
SCHEMBL5440304 0.81 TSHR (0.73) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1
SCHEMBL12018050 0.81 PTPN1 (0.73) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1
SCHEMBL11193183 0.81 SMN1; SMN2 (0.65) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1
SCHEMBL16922181 0.80 NPC1 (0.66) SMN1; SMN2HPGDRAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121731264-A Application of 2-chloro-N- (4-isopropylphenyl) acetamide and pharmaceutically acceptable salt thereof and mycobacterium tuberculosis inhibitor 浙江省疾病预防控制中心(浙江省预防医学科学院) 2026-03-27 — — CN disclosed
CN-121731264-A Application of 2-chloro-N- (4-isopropylphenyl) acetamide and pharmaceutically acceptable salt thereof and mycobacterium tuberculosis inhibitor 浙江省疾病预防控制中心(浙江省预防医学科学院) 2026-03-27 — — CN disclosed
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2024-01-18 — — US disclosed
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2024-01-18 — — US disclosed
CN-113429356-B Triazole sulfonamide derivative and application thereof in agriculture 东莞市东阳光农药研发有限公司 2024-01-16 — — CN disclosed
CN-116438167-A Compounds having O-GlcNAc enzyme inhibitory activity and uses thereof 美迪福伦DBT有限公司 2023-07-14 — — CN disclosed
US-20230136150-A1 Compositions for Inhibition of Insect Sensing UNIV VANDERBILT (US) 2023-05-04 — — US disclosed
US-20230136150-A1 Compositions for Inhibition of Insect Sensing UNIV VANDERBILT (US) 2023-05-04 — — US disclosed
CN-109265451-B Butyrylcholinesterase selective inhibitor and preparation method and application thereof 中国药科大学 2022-07-15 — — CN disclosed
CN-113429356-A Triazole sulfonamide derivative and application thereof in agriculture 东莞市东阳光农药研发有限公司 2021-09-24 — — CN disclosed
EP-0884304-A2 Process for the preparation of F-(4-Fluoro-phenyl)-N-isopropyl-chloracetamide BAYER AG (DE) 1998-12-16 — — EP disclosed
US-5831126-A FROM CHLOROACETYL CHLORIDE AND P-FLUORO-N-ISOPROPYLANILINE BAYER AKTIENGESELLSCHAFT (DE) 1998-11-03 — — US disclosed
US-5639713-A Herbicidal compositions based on N-(4-fluoro-phenyl)-N-isopropyl-chloroacetamide, and process for the preparation of this compound BAYER AKTIENGESELLSCHAFT (DE) 1997-06-17 — — US disclosed
EP-0709368-A1 Herbicidal agent based on the N-(4-fluorphenyl)-N-isopropyl-chloroacetamide and process for its preparation BAYER AG (DE) 1996-05-01 — — EP disclosed
EP-0083613-B1 N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES MAY & BAKER LIMITED (GB) 1988-06-01 — — EP disclosed
US-4629495-A Herbicidal 5-amino-4-cyano-1-phenylpyrazoles MAY & BAKER LIMITED (GB) 1986-12-16 — — US disclosed
US-4496390-A WEED-CONTRTOLLING HERBICIDES MAY & BAKER LIMITED (GB) 1985-01-29 — — US disclosed
US-4459150-A 5-Acylamino-4-cyano-1-phenylpyrazole derivatives and use as herbicides MAY & BAKER LIMITED (GB) 1984-07-10 — — US disclosed
EP-0083613-A1 N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES. MAY & BAKER LTD (GB) 1983-07-20 — — EP disclosed
WO-1983000332-A1 N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES MAY & BAKER LTD (GB) 1983-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230136150-A1 Compositions for Inhibition of Insect Sensing OR51E2, TRPA1, OR10J3 SMN1; SMN2 4423/4885HPGD 4384/4885RAB9A 3172/4885
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF OGA, OGT, ENGASE SMN1; SMN2 4435/4885HPGD 3738/4885RAB9A 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.