SCHEMBL25848971

SCHEMBL25848971

CCCCCCCCCCCCCCCC(=O)NCCOCCCNC(=O)c1cc(OCCNC(=O)OC(C)(C)C)cc(C(=O)NCCOCCNC(=O)CCCCCCCCCCCCCCC)c1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 13/20 0.49
CNR2 P34972 12/20 0.49
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
KMT2A Q03164 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25835758 0.98 CNR1 (0.51) CNR1CNR2MAPTSMN1; SMN2MEN1
SCHEMBL25849055 0.88 GAA (0.44) MAPTGAASMN1; SMN2MEN1KMT2A
SCHEMBL18874911 0.82 TDP1 (0.54) CA12CA1CA2CA9
SCHEMBL16524095 0.82 FAAH (0.50) CNR1CNR2CA12CA1CA2
SCHEMBL26032408 0.82 FAAH (0.50) CNR1CNR2CA12CA1CA2
SCHEMBL28843534 0.82 FAAH (0.50) CNR1CNR2CA12CA1CA2
SCHEMBL25835507 0.82 FAAH (0.50) CNR1CNR2CA12CA1CA2
SCHEMBL23475931 0.81 FAAH (0.49) CNR1CNR2CA12CA1CA2
SCHEMBL32680127 0.81 FAAH (0.49) CNR1CNR2CA12CA1CA2
SCHEMBL23475914 0.81 FAAH (0.49) CNR1CNR2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 CNR1 4510/4885CNR2 4584/4885MAPT 3973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.