SCHEMBL25849027

SCHEMBL25849027

CCCCCCCCC(CCCCCC)C(=O)NCCCOCCNC(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
GAA P10253 1/20 0.51
TDP1 Q9NUW8 1/20 0.47
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
TLR2 O60603 2/20 0.41
EPHX1 P07099 1/20 0.41
POLB P06746 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CTSS P25774 1/20 0.40
CTSK P43235 1/20 0.40
GLP1R P43220 3/20 0.39
GNAI3 P08754 1/20 0.39
GNAO1 P09471 1/20 0.39
GNAI1 P63096 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25848706 1.00 MEN1 (0.51) MEN1KMT2AGAATDP1CA12
SCHEMBL26033023 0.96 MEN1 (0.51) MEN1KMT2AGAATDP1CA12
SCHEMBL25835742 0.95 MEN1 (0.50) MEN1KMT2AGAATDP1CA12
SCHEMBL25845557 0.93 MEN1 (0.45) MEN1KMT2AGAATDP1CA12
SCHEMBL25849055 0.87 GAA (0.44) MEN1KMT2AGAATDP1CA12
SCHEMBL31021593 0.85 TDP1 (0.54) MEN1KMT2AGAATDP1CA12
SCHEMBL16569093 0.84 TDP1 (0.53) MEN1KMT2AGAATDP1CA12
SCHEMBL12706042 0.84 MEN1 (0.46) MEN1KMT2AGAATDP1CA12
SCHEMBL13790284 0.82 DPP7 (0.54) MEN1KMT2AGAATDP1MAOA
SCHEMBL20363983 0.82 TDP1 (0.63) MEN1KMT2AGAATDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 MEN1 4753/4885KMT2A 1603/4885GAA 201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.