SCHEMBL25845557

SCHEMBL25845557

CCCCCCCCC(CCCCCC)C(=O)NCCCOCCNC(=O)CCOCCNC(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
GAA P10253 1/20 0.45
GLP1R P43220 8/20 0.44
TDP1 Q9NUW8 1/20 0.41
CAPN1 P07384 1/20 0.40
CASP2 P42575 1/20 0.39
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
TLR2 O60603 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
BIRC2 Q13490 1/20 0.37
NAAA Q02083 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25848706 0.93 MEN1 (0.51) MEN1KMT2AGAAGLP1RTDP1
SCHEMBL25849027 0.93 MEN1 (0.51) MEN1KMT2AGAAGLP1RTDP1
SCHEMBL26033023 0.90 MEN1 (0.51) MEN1KMT2AGAAGLP1RTDP1
SCHEMBL25835742 0.89 MEN1 (0.50) MEN1KMT2AGAAGLP1RTDP1
SCHEMBL17921740 0.88 CA14 (0.42) MEN1KMT2AGAAGLP1RTDP1
SCHEMBL16351212 0.86 TDP1 (0.46) MEN1KMT2AGAATDP1CASP2
SCHEMBL25835309 0.85 FAAH (0.48) TDP1CASP2CA12CA1CA2
SCHEMBL25835294 0.85 FAAH (0.48) TDP1CASP2CA12CA1CA2
SCHEMBL25067424 0.84 FAAH (0.47) GLP1RTDP1CASP2
SCHEMBL25067291 0.84 FAAH (0.47) GLP1RTDP1CASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 MEN1 4753/4885KMT2A 1603/4885GAA 201/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 MEN1 4828/4885KMT2A 3122/4885GAA 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.