SCHEMBL25849054

SCHEMBL25849054

CC1(C)c2ccccc2Oc2ccc(-c3cccc4c3C(C)(C)c3ccccc3-4)cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 8/20 0.33
CTSD P07339 4/20 0.33
BACE1 P56817 4/20 0.33
DRD1 P21728 2/20 0.33
RARB P10826 2/20 0.32
RXRA P19793 2/20 0.32
RARG P13631 1/20 0.32
PGR P06401 3/20 0.31
RARA P10276 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
MLNR O43193 1/20 0.30
NR1I2 O75469 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRB1 P08588 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849156 0.91 FTO (0.33) PDK2DRD1RARBRXRARARG
SCHEMBL25849428 0.89 PDK2 (0.36) PDK2CTSDBACE1DRD1RARB
SCHEMBL25872288 0.88 PDK2 (0.38) PDK2CTSDBACE1RARBRXRA
SCHEMBL25849430 0.87 PDK2 (0.38) PDK2
SCHEMBL25848894 0.86 CTSD (0.33) PDK2CTSDBACE1DRD1PGR
SCHEMBL25871488 0.86 PDK2 (0.40) PDK2BACE1PGR
SCHEMBL25848909 0.85 DRD1 (0.33) PDK2CTSDBACE1DRD1
SCHEMBL25872804 0.85 PDK2 (0.40) PDK2BACE1
SCHEMBL25872197 0.83 CTSD (0.32) CTSDBACE1DRD1RARBRXRA
SCHEMBL13557543 0.83 BACE1 (0.36) CTSDBACE1DRD1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed