Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962299 | 0.97 | RAF1 (0.35) | TNIKRAF1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25605286 | 0.97 | RAF1 (0.33) | TNIKRAF1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3953603 | 0.97 | SMN1; SMN2 (0.33) | TNIKRAF1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25716497 | 0.95 | TNIK (0.37) | TNIKRAF1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25605288 | 0.93 | LMNA (0.36) | TNIKRAF1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25716498 | 0.93 | TNIK (0.35) | TNIKRAF1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1186527 | 0.92 | MEN1 (0.34) | TNIKRAF1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL26514172 | 0.92 | NPSR1 (0.35) | TNIKRAF1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25716494 | 0.91 | TNIK (0.30) | TNIK | |
| SCHEMBL25718161 | 0.91 | LMNA (0.34) | RAF1SMN1; SMN2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269532-A1 | PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | Hoya Lens Thailand Ltd. (TH) | 2023-11-01 | — | — | EP | disclosed |
| EP-4270067-A1 | PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND GLASSES | Hoya Lens Thailand Ltd. (TH) | 2023-11-01 | — | — | EP | disclosed |
| US-20230340318-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | HOYA LENS THAILAND LTD. (TH) | 2023-10-26 | — | — | US | disclosed |
| US-20230227717-A1 | PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230340318-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | NR2E3, CRY1, RPS10 | TNIK 4867/4885RAF1 2643/4885SMN1; SMN2 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.