Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | SDHB | P21912 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19047179 | 0.90 | BRD4 (0.45) | NR1H2NR1H3BRD4KIF11CREBBP | |
| SCHEMBL25849453 | 0.90 | BRD4 (0.41) | NR1H2NR1H3BRD4CREBBP | |
| SCHEMBL19032107 | 0.89 | SLC2A1 (0.43) | BRD4MAPTNPSR1KDM4EMEN1 | |
| SCHEMBL25849408 | 0.88 | BRD4 (0.45) | BRD4ADAMTS5CREBBPMAPTHTT | |
| SCHEMBL25849454 | 0.86 | SLC2A1 (0.49) | BRD4CREBBPKDM4EMEN1KMT2A | |
| SCHEMBL24046937 | 0.85 | BRD4 (0.45) | NR1H2NR1H3BRD4CREBBPTP53 | |
| SCHEMBL19047356 | 0.84 | SLC2A1 (0.39) | BRD4CREBBP | |
| SCHEMBL25849457 | 0.83 | BRD4 (0.44) | NR1H2NR1H3BRD4ADAMTS5CREBBP | |
| SCHEMBL25849459 | 0.83 | BRD4 (0.41) | NR1H2NR1H3BRD4CREBBPKDM4E | |
| SCHEMBL19032127 | 0.82 | SLC2A1 (0.41) | BRD4CREBBPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | THE UNIVERSITY OF SHEFFIELD (GB) | 2023-06-15 | — | — | US | disclosed |
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | THE UNIVERSITY OF SHEFFIELD (GB) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | CYP11B2, CYP11B1, COX5B | NR1H2 191/4885NR1H3 238/4885BRD4 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.