Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 5/20 | 0.46 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19032056 | 0.91 | SLC2A1 (0.47) | PDE9ASLC2A1BRD4CUL4AALDH1A1 | |
| SCHEMBL19032069 | 0.90 | SLC2A1 (0.46) | PDE9ASLC2A1BRD4CUL4AALDH1A1 | |
| SCHEMBL19032086 | 0.90 | SLC2A1 (0.62) | PDE9ASLC2A1BRD4CUL4AALDH1A1 | |
| SCHEMBL25849408 | 0.88 | BRD4 (0.45) | PDE9ASLC2A1BRD4MAPTBCHE | |
| SCHEMBL19032416 | 0.88 | SLC2A1 (0.53) | PDE9ASLC2A1BRD4CUL4AALDH1A1 | |
| SCHEMBL19032107 | 0.87 | SLC2A1 (0.43) | PDE9ASLC2A1BRD4CUL4AALDH1A1 | |
| SCHEMBL19032098 | 0.87 | BRD4 (0.44) | PDE9ASLC2A1BRD4CUL4AALDH1A1 | |
| SCHEMBL19032058 | 0.87 | SLC2A1 (0.43) | PDE9ASLC2A1BRD4CUL4AALDH1A1 | |
| SCHEMBL19032141 | 0.86 | SLC2A1 (0.48) | PDE9ASLC2A1BRD4CUL4AALDH1A1 | |
| SCHEMBL29768840 | 0.86 | SLC2A1 (0.48) | PDE9ASLC2A1BRD4CUL4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | THE UNIVERSITY OF SHEFFIELD (GB) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | CYP11B2, CYP11B1, COX5B | PDE9A 1605/4885SLC2A1 4289/4885BRD4 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.