SCHEMBL25849713

SCHEMBL25849713

CN1C(=O)S/C(=C\c2ccc3c4c(ccc3c2)N(C)c2ccccc2C4(C)C)C1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
MYC P01106 1/20 0.37
PTPN1 P18031 1/20 0.37
ACP1 P24666 1/20 0.37
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.36
POLB P06746 2/20 0.36
THRB P10828 2/20 0.36
MAPK1 P28482 2/20 0.36
RECQL P46063 2/20 0.36
BLM P54132 2/20 0.36
USP2 O75604 1/20 0.36
S100A4 P26447 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849714 0.85 MYC (0.42) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL25849789 0.81 MAPT (0.42) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL25849723 0.81 NR1H4 (0.44) MEN1MAPTKMT2AALDH1A1POLB
SCHEMBL25849707 0.80 MAPT (0.39) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL25849731 0.74 KMT2A (0.36) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL25849739 0.73 MEN1 (0.39) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL25849766 0.73 KMT2A (0.37) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL25849719 0.73 MEN1 (0.32) RAB9AMEN1MAPTKMT2AALDH1A1
SCHEMBL17430638 0.72 MAPT (0.50) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL17430639 0.72 PTPN1 (0.43) PTPN1MEN1MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed