SCHEMBL25849714

SCHEMBL25849714

CN1C(=O)S/C(=C\c2ccc3c(c2)C(C)(C)c2ccccc2N3C)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.42
CISD1 Q9NZ45 2/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
MEN1 O00255 5/20 0.41
MAPT P10636 5/20 0.41
KMT2A Q03164 5/20 0.41
POLB P06746 3/20 0.41
THRB P10828 3/20 0.41
MAPK1 P28482 3/20 0.41
RECQL P46063 3/20 0.41
BLM P54132 3/20 0.41
RAB9A P51151 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
ALDH1A1 P00352 2/20 0.41
USP2 O75604 1/20 0.41
S100A4 P26447 1/20 0.41
NPC1 O15118 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849713 0.85 RAB9A (0.38) MYCCISD1MAOAMAOBMEN1
SCHEMBL25165793 0.82 MEN1 (0.57) MEN1MAPTKMT2APOLBTHRB
SCHEMBL25849718 0.80 MYC (0.41) MYCCISD1MAOAMAOBMEN1
SCHEMBL22826063 0.78 KMT2A (0.67) MEN1MAPTKMT2APOLBTHRB
SCHEMBL22177582 0.77 MAPT (0.47) MEN1MAPTKMT2APOLBTHRB
SCHEMBL25849726 0.76 NR1H4 (0.47) MEN1MAPTKMT2APOLBTHRB
SCHEMBL22177571 0.76 PDE4B (0.48) CISD1MAOAMAOBMEN1MAPT
SCHEMBL22177580 0.74 MAPT (0.42) MEN1MAPTKMT2APOLBTHRB
SCHEMBL22177499 0.73 MAPT (0.39) MEN1MAPTKMT2APOLBTHRB
SCHEMBL22177500 0.73 MAPT (0.39) MEN1MAPTKMT2APOLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed