SCHEMBL25849788

SCHEMBL25849788

CN1c2ccccc2C2(c3ccccc3-c3ccccc32)c2cc(C=C3C(=O)c4cc5ccccc5cc4C3=O)sc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.37
KMT2A Q03164 7/20 0.37
ALDH1A1 P00352 5/20 0.37
HPGD P15428 3/20 0.37
THRB P10828 1/20 0.37
RECQL P46063 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HTT P42858 4/20 0.35
MEN1 O00255 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
USP2 O75604 3/20 0.35
POLB P06746 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
STAT3 P40763 1/20 0.34
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849711 0.87 MAPT (0.41) MAPTKMT2AALDH1A1HPGDTHRB
SCHEMBL23331772 0.85 ALDH1A1 (0.33) MAPTKMT2AALDH1A1HPGDTHRB
SCHEMBL25849792 0.81 MAPT (0.46) MAPTKMT2AALDH1A1HPGDTHRB
SCHEMBL25849786 0.80 LCK (0.39) MAPTKMT2AALDH1A1HTTMEN1
SCHEMBL26400043 0.78 KMT2A (0.38) MAPTKMT2AALDH1A1HPGDTHRB
SCHEMBL23331193 0.78 ALDH1A1 (0.39) MAPTKMT2AALDH1A1HPGDTHRB
SCHEMBL23331587 0.78 KMT2A (0.38) MAPTKMT2AALDH1A1HPGDTHRB
SCHEMBL23331438 0.77 KMT2A (0.41) MAPTKMT2AALDH1A1HPGDTHRB
SCHEMBL25849745 0.77 MAPT (0.32) MAPTKMT2AALDH1A1HPGDTHRB
SCHEMBL23331636 0.77 ALDH1A1 (0.33) MAPTKMT2AALDH1A1HPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed