SCHEMBL25849745

SCHEMBL25849745

CN1c2ccc(-c3ccccc3)cc2C(C)(C)c2cc(C=C3C(=O)c4cc5ccccc5cc4C3=O)sc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.32
KMT2A Q03164 3/20 0.32
ALDH1A1 P00352 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.32
RECQL P46063 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
POLB P06746 2/20 0.31
MEN1 O00255 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
USP2 O75604 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
PTGS2 P35354 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850660 0.89 ALDH1A1 (0.32) MAPTKMT2AALDH1A1THRBHPGD
SCHEMBL25849755 0.89 POLB (0.33) MAPTKMT2AALDH1A1THRBHPGD
SCHEMBL25849750 0.89 ALDH1A1 (0.32) MAPTKMT2AALDH1A1THRBHPGD
SCHEMBL25849765 0.88 CREBBP (0.32) PDE4APDE4BPDE4CPDE4DCREBBP
SCHEMBL25849711 0.87 MAPT (0.41) MAPTKMT2AALDH1A1THRBHPGD
SCHEMBL25849760 0.86 ALDH1A1 (0.31) MAPTKMT2AALDH1A1THRBHPGD
SCHEMBL25849768 0.85 NR1H3 (0.34) MAPTKMT2AALDH1A1THRBHPGD
SCHEMBL22177616 0.83 BCL2 (0.36) MAPTKMT2AALDH1A1HPGDTDP1
SCHEMBL25849792 0.80 MAPT (0.46) MAPTKMT2AALDH1A1THRBHPGD
SCHEMBL25850000 0.78 PGR (0.35) MAPTKMT2AALDH1A1THRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed