Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355204 | 0.79 | PLAU (0.47) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL12232242 | 0.76 | CCR1 (0.52) | KDM4ETDP1PLAUAURKAADRA2A | |
| SCHEMBL12687394 | 0.76 | DYRK1B (0.38) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL4987651 | 0.73 | KDM4E (0.38) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL25849880 | 0.72 | EGFR (0.38) | ALDH1A1KDM4EMAPTEGFR | |
| SCHEMBL31505353 | 0.72 | PARP1 (0.41) | ALDH1A1HRH3 | |
| SCHEMBL169260 | 0.69 | MAPT (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL29859744 | 0.69 | MAPT (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL30283008 | 0.69 | MAPT (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL1073946 | 0.69 | CCR1 (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133225-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |