Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 5/20 | 0.36 |
| ▸ | NCF1 | P14598 | 6/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NCK1 | P16333 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819657 | 0.79 | BACE1 (0.50) | PLAUBACE1NCF1NOS2KDM4E | |
| SCHEMBL30473687 | 0.79 | BACE1 (0.50) | PLAUBACE1NCF1NOS2KDM4E | |
| SCHEMBL25849805 | 0.79 | MEN1 (0.33) | PLAUKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL25433801 | 0.77 | BACE1 (0.47) | PLAUBACE1KDM4E | |
| SCHEMBL4987651 | 0.76 | KDM4E (0.38) | PLAUKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL20020755 | 0.75 | PLAU (0.44) | PLAUBACE1NCF1 | |
| SCHEMBL24254225 | 0.75 | MCHR1 (0.35) | PLAUBACE1NCF1NOS2KDM4E | |
| SCHEMBL24091982 | 0.75 | NOS1 (0.43) | BACE1NCF1NOS2KMT2AALDH1A1 | |
| SCHEMBL22521385 | 0.75 | BACE1 (0.39) | PLAUBACE1NCF1NOS2KDM4E | |
| SCHEMBL22509842 | 0.75 | DHFR (0.38) | PLAUBACE1NCF1NOS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015900-A1 | Aromatic amide polymer systems and methods for making the same | FOWKES STEVEN W | 2007-01-18 | — | — | US | disclosed |
| US-7160978-B2 | Aromatic amide polymer systems and methods for making the same | FOWKES STEVEN W | 2007-01-09 | — | — | US | disclosed |
| EP-1601710-A4 | AROMATIC AMIDE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME | FOWKES STEVEN W (US) | 2006-03-29 | — | — | EP | disclosed |
| EP-1601710-A2 | AROMATIC AMIDE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME | Fowkes, Steven W. (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2005005486-A2 | AROMATIC AMIDE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME | FOWKES STEVEN W (US) | 2005-01-20 | — | — | WO | disclosed |
| US-20040171756-A1 | Aromatic amide polymer systems and methods for making the same | FOWKES STEVEN W (US) | 2004-09-02 | — | — | US | disclosed |