Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28091589 | 0.80 | NCF1 (0.41) | EGFRALDH1A1MAPTMCHR1DHFR | |
| SCHEMBL12232242 | 0.76 | CCR1 (0.52) | KDM4E | |
| SCHEMBL19445081 | 0.73 | ACP1 (0.50) | EGFRKDM4EALDH1A1MAPTACP1 | |
| SCHEMBL12687394 | 0.72 | DYRK1B (0.38) | KDM4EALDH1A1MAPT | |
| SCHEMBL25849805 | 0.72 | MEN1 (0.33) | EGFRKDM4EALDH1A1MAPT | |
| SCHEMBL21646385 | 0.71 | EGFR (0.38) | EGFRMAPTACP1 | |
| SCHEMBL13059757 | 0.70 | — | — | |
| SCHEMBL31505353 | 0.68 | PARP1 (0.41) | ALDH1A1 | |
| SCHEMBL25124423 | 0.67 | EGFR (0.56) | EGFRKDM4EALDH1A1MAPT | |
| SCHEMBL20095380 | 0.66 | BRAF (0.40) | EGFRKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133225-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |