Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127261 | 0.75 | MAPT (0.53) | NOTUMMAPTMEN1KMT2ANPC1 | |
| SCHEMBL29139363 | 0.74 | ERN1 (0.40) | C1RNOTUMERN1GUSBAPEX1 | |
| SCHEMBL11441284 | 0.71 | GABRA1 (0.41) | NISCHALDH1A1 | |
| SCHEMBL30726718 | 0.70 | MAPT (0.41) | C1RCCNE2CCNE1CDK2MAPT | |
| SCHEMBL2478500 | 0.70 | MEN1 (0.52) | ERN1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL29547174 | 0.69 | ACHE (0.47) | NOTUMMAPTIDO1DCUN1D1PTPRC | |
| SCHEMBL197834 | 0.69 | ACHE (0.47) | NOTUMMAPTIDO1DCUN1D1PTPRC | |
| Hydrogen Sulfide SCHEMBL10700223 | 0.67 | ACHE (0.45) | NOTUMMAPTIDO1DCUN1D1PTPRC | |
| SCHEMBL30389980 | 0.67 | PTPRC (0.48) | NOTUMMAPTIDO1DCUN1D1PTPRC | |
| SCHEMBL5706297 | 0.67 | PTPRC (0.48) | NOTUMMAPTIDO1DCUN1D1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793990-B1 | ANTIBACTERIAL COMPOUNDS | INFEX THERAPEUTICS LTD (GB) | 2023-07-19 | — | — | EP | disclosed |