Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 11/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25844205 | 0.74 | POLB (0.38) | GRM5NAMPTGABRG2GABRB3GABRA5 | |
| SCHEMBL17888262 | 0.74 | NAMPT (0.53) | GRM5NAMPTKMT2ACNR2 | |
| SCHEMBL25853617 | 0.74 | CHRM1 (0.35) | — | |
| SCHEMBL25849396 | 0.73 | RECQL (0.50) | KMT2APOLBMAPTHTT | |
| SCHEMBL25848587 | 0.70 | RIPK1 (0.35) | NAMPTCNR2 | |
| SCHEMBL25853513 | 0.69 | — | — | |
| SCHEMBL25853250 | 0.69 | GRM5 (0.39) | GRM5NAMPTGABRG2GABRB3GABRA5 | |
| SCHEMBL13013114 | 0.68 | HPGD (0.57) | NAMPTCNR2HTT | |
| SCHEMBL12385902 | 0.67 | KMT2A (0.46) | NAMPTKMT2ACNR2 | |
| SCHEMBL21584689 | 0.67 | HTT (0.54) | NAMPTCNR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |